101 College Street

101 College Street is a $250 million, state-of-the-art life sciences building completed in the fall of 2023.

The 525,000 SF, ten-story lab building is anchored by Yale University and Connecticut-bred life sciences company Alexion Pharmaceuticals (a subsidiary of AstraZeneca). Additionally, the building includes a 52,000-square-foot, world-class incubator leased to BioLabs to foster life sciences start-up companies in Connecticut, lab-classroom space for New Haven Public Schools, and public open space.

The project is a critical extension of the City of New Haven’s Downtown Crossing initiative, which involved dismantling Route 34, reclaiming 12 developable acres to support the growing life sciences industry, and reconnecting the Medical District, Union Station, and the City's Central Business District.