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Developer Carter Winstanley has spent the last 22 years working to build up a life science hub in New Haven. In the beginning, he set a modest benchmark for success.

Two decades later, 300 George is at capacity, and two subsequent Winstanley bioscience buildings — 25 Science Park and 100 College St., home of Alexion Pharmaceuticals — are also full.

This spring, he plans to kick off construction on a second bioscience tower at 101 College St., set to open in 2023, and he is finalizing deals with major tenants.